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1
Use of nuclear Overhauser effect in the study of peptides and proteins.
Biochimie. 1980;62(11-12):753-73. doi: 10.1016/s0300-9084(80)80131-3.
2
The quantitation of nuclear Overhauser effect methods for total conformational analysis of peptides in solution. Application to gramicidin S.溶液中肽段全构象分析的核Overhauser效应方法定量。应用于短杆菌肽S。
Biophys J. 1978 Dec;24(3):815-32. doi: 10.1016/S0006-3495(78)85422-8.
3
Intramolecular 1H nuclear Overhauser effect study of the solution conformation of valinomycin in dimethyl sulfoxide.在二甲基亚砜中缬氨霉素溶液构象的分子内1H核Overhauser效应研究
Biochemistry. 1976 Dec 28;15(26):5721-9. doi: 10.1021/bi00671a007.
4
Two-dimensional transferred nuclear Overhauser effect spectroscopy (TRNOESY) studies of nucleotide conformations in creatine kinase complexes: effects due to weak nonspecific binding.肌酸激酶复合物中核苷酸构象的二维转移核Overhauser效应光谱（TRNOESY）研究：弱非特异性结合的影响
Biochemistry. 1993 Nov 30;32(47):12941-8. doi: 10.1021/bi00210a049.
5
Solution conformation of peptides by the intramolecular nuclear Overhauser effect experiment. Study of valinomycin-K+.通过分子内核Overhauser效应实验研究肽的溶液构象。缬氨霉素-K⁺的研究
Biophys J. 1978 Dec;24(3):791-814. doi: 10.1016/S0006-3495(78)85421-6.
6
Binding of adenosine 5'-diphosphate to creatine kinase. An investigation using intermolecular nuclear Overhauser effect measurements.腺苷5'-二磷酸与肌酸激酶的结合。一项使用分子间核Overhauser效应测量的研究。
Biochemistry. 1976 Oct 19;15(21):4724-30. doi: 10.1021/bi00666a029.
7
Systematic study of nuclear Overhauser effects vis-à-vis local helical parameters, sugar puckers, and glycosidic torsions in B DNA: insensitivity of NOE to local transitions in B DNA oligonucleotides due to internal structural compensations.关于B型DNA中核Overhauser效应与局部螺旋参数、糖环构象和糖苷键扭转的系统研究：由于内部结构补偿，核Overhauser效应对B型DNA寡核苷酸局部转变不敏感。
Biochemistry. 1992 Apr 28;31(16):3918-30. doi: 10.1021/bi00131a005.
8
Specificity of interproton nuclear Overhauser effects in gramicidin-S dissolved in deuterated ethylene glycol.溶解于氘代乙二醇中的短杆菌肽-S中质子间核Overhauser效应的特异性
Biophys J. 1978 Dec;24(3):779-90. doi: 10.1016/S0006-3495(78)85420-4.
9
NMR studies of the MgATP binding site of adenylate kinase and of a 45-residue peptide fragment of the enzyme.腺苷酸激酶的MgATP结合位点及该酶一个45个残基的肽片段的核磁共振研究。
Biochemistry. 1985 Aug 13;24(17):4680-94. doi: 10.1021/bi00338a030.
10
Structure of apamin in solution: a two-dimensional nuclear magnetic resonance study.蜂毒明肽在溶液中的结构：二维核磁共振研究
Biochemistry. 1983 Apr 12;22(8):1901-6. doi: 10.1021/bi00277a025.

引用本文的文献

1
Overhauser enhanced magnetic resonance imaging for tumor oximetry: coregistration of tumor anatomy and tissue oxygen concentration.用于肿瘤血氧测定的奥弗豪泽增强磁共振成像：肿瘤解剖结构与组织氧浓度的配准
Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):2216-21. doi: 10.1073/pnas.042671399.

Use of nuclear Overhauser effect in the study of peptides and proteins.

作者信息

Roques B P, Rao R, Marion D

出版信息

Biochimie. 1980;62(11-12):753-73. doi: 10.1016/s0300-9084(80)80131-3.

DOI:10.1016/s0300-9084(80)80131-3
PMID:6162486
Abstract

The nuclear Overhauser effect (NOE) leads to changes in the intensity of signal(s) of a set of nuclei as a function of their respective distances. The use of NOE allows to obtain structural informations on peptides and proteins in solution as well as the study of interactions between small ligands and biomolecules. In this review, aspects of the basic theory of the NOE will be presented and the more recent applications of homonuclear and heteronuclear NOE's in biomolecules will be surveyed. Typical examples will be illustrated and limitations of the method will be discussed.

摘要