[Isolation of a cellular hybrid secreting an antibody specific for human leukocyte interferon].
作者信息
Montagnier L, Laurent A G, Gruest J
出版信息
C R Seances Acad Sci D. 1980 Nov 24;291(11):893-6.
PMID:6162583
Abstract
A cellular hybrid secreting a Mouse monoclonal immunoglobulin (IgG) specific of human leukocyte interferon has been obtained, following fusion of a nonsecreting variant of the myeloma P3X63 Ag8 with splenic lymphocytes from a Mouse immunized against interferon incorporated into liposomes. The antibody also recognizes human interferon made by a bacterial recombinant and a fraction of interferon made by Namalva cells. Mass production of the antibody has been achieved using ascitic growth of the hybrid in Mice.
摘要
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[Isolation of a cellular hybrid secreting an antibody specific for human leukocyte interferon].
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