在棕榈酸甲酯对网状内皮系统的实验作用过程中热损伤大鼠红细胞的隔离
Sequestration of heat damaged rat erythrocytes during experimental action of methyl palmitate on RES.
作者信息
Sebestík V
出版信息
Folia Haematol Int Mag Klin Morphol Blutforsch. 1980;107(5):778-81.
PMID:6162745
Abstract
The effect of an i.v. injection of methyl palmitate emulsion (MP) on the clearance of heat damaged erythrocytes from the blood and their sequestration in organs of rats was followed. Twenty-four hours following application of MP in the dose of 1.5 g/kg of body weight the survival half time of erythrocytes (T1/2(51)Cr) significantly increased, whereas the amount of sequestrated red cells in the spleen decreased. The subsequent intervals of examination, however, showed no differences as compared to the controls.
摘要
静脉注射棕榈酸甲酯乳剂（MP）对热损伤红细胞从大鼠血液中的清除及其在大鼠器官中的滞留作用进行了跟踪研究。在以1.5 g/kg体重的剂量施用MP后24小时，红细胞的存活半衰期（T1/2(51)Cr）显著增加，而脾脏中滞留的红细胞数量减少。然而，后续的检查间隔与对照组相比没有差异。
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