Sebestík V, Brabec V
Folia Haematol Int Mag Klin Morphol Blutforsch. 1979;106(2):224-31.
The authors attempted at experimental elimination of sequestration function of the spleen in Wistar rats using an i.v. injection of ethyl palmitate emulsion, both in "hypersplenic" animals being long-term applied i.p. methyl cellulose solution, and in control rats. In the rats clearance of 51Cr-labelled and thermally damaged erythrocytes from blood was examined and their sequestration in the spleen and liver followed. The ethyl palmitate injection resulted in both experimental groups in a significant decrease of the erythrocyte counts sequestrated in the spleen, and significant prolongation of the elimination half time for thermally damaged erythrocytes from the blood.
作者试图通过静脉注射棕榈酸乙酯乳剂，在长期腹腔注射甲基纤维素溶液的“脾功能亢进”动物和对照大鼠中，实验性消除Wistar大鼠脾脏的隔离功能。检测大鼠血液中51Cr标记的热损伤红细胞的清除情况，并追踪其在脾脏和肝脏中的隔离情况。注射棕榈酸乙酯后，两个实验组脾脏中隔离的红细胞计数均显著降低，血液中热损伤红细胞的清除半衰期显著延长。
