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关于人类15号染色体的结构与多态性

On the structure and polymorphism of the human chromosome no. 15.

作者信息

Wachtler F, Musil R

出版信息

Hum Genet. 1980;56(1):115-8. doi: 10.1007/BF00281580.

DOI:10.1007/BF00281580
PMID:6162775
Abstract

Chromosome preparations from 67 randomly selected healthy individuals were consecutively stained with silver, mithramycin, pentamidine-DAPI, and quinacrine mustard. In the short arm of the chromosome 15 up to six regions, which were highly polymorphic, apparently independently of each other, could be detected by the given methods. The frequency of occurrence of each individual polymorphic feature in the population investigated ranges from 70% to 87%. They appear randomly and independently of each other.

摘要

从67名随机挑选的健康个体中制备染色体标本，依次用银染、放线菌素D、喷他脒 - 二氨基苯基吲哚（DAPI）和喹吖因芥子气进行染色。在15号染色体短臂上，通过给定方法可检测到多达六个高度多态性的区域，这些区域显然彼此独立。在所研究的人群中，每个个体多态性特征的出现频率在70%至87%之间。它们随机出现且彼此独立。

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1
On the structure and polymorphism of the human chromosome no. 15.关于人类15号染色体的结构与多态性
Hum Genet. 1980;56(1):115-8. doi: 10.1007/BF00281580.
2
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引用本文的文献

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Preferential fluorescent staining of heterochromatic regions in human chromosomes 9, 15, and the Y by D 287/170.D 287/170对人类9号、15号染色体以及Y染色体上异染色质区域的优先荧光染色。
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Polymorphism of 5-methylcytosine-rich DNA in human acrocentric chromosomes.人类近端着丝粒染色体中富含5-甲基胞嘧啶的DNA的多态性
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Aspects of evaluation, significance, and evolution of human C-band heteromorphism.人类C带异态性的评估、意义及进化方面

本文引用的文献

1
Demonstration of a non-RNA nucleolar fraction by silver staining.通过银染法显示非RNA核仁组分。
Exp Cell Res. 1962 Mar;26:428-31. doi: 10.1016/0014-4827(62)90195-7.
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Cytochemical studies of metaphase chromosomes by flow cytometry.中期染色体的流式细胞术细胞化学研究。
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Quantitative analysis of fluorescence profiles of chromosomes. Influence of DNA base composition on banding.染色体荧光图谱的定量分析。DNA碱基组成对显带的影响。
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Parental origin of chromosome 15 deletion in Prader-Willi syndrome.普拉德-威利综合征中15号染色体缺失的亲本来源
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Intensity heteromorphisms of human chromosome 15p by DA/DAPI technique.
Hum Genet. 1986 Aug;73(4):298-300. doi: 10.1007/BF00279089.
Exp Cell Res. 1980 Feb;125(2):251-64. doi: 10.1016/0014-4827(80)90121-4.
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[Polymorphisms of the human chromosome no. 15 (author's transl)].人类第15号染色体的多态性（作者译）
Wien Klin Wochenschr. 1980 Nov 7;92(21):761-4.
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Abundance of protein-bound sulfhydryl and disulfide groups at chromosomal nucleolus organizing regions: a cytochemical study on the selective silver staining of NORs.染色体核仁组织区蛋白质结合的巯基和二硫基团的丰度：核仁组织区选择性银染的细胞化学研究
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Human chromosomal heteromorphisms: nature and clinical significance.人类染色体异态性：本质与临床意义
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7
Effects of counterstaining with DNA binding drugs on fluorescent banding patterns of human and mammalian chromosomes.用DNA结合药物复染对人类和哺乳动物染色体荧光带型的影响。
Eur J Cell Biol. 1980 Feb;20(3):290-6.
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5-Methylcytosine localised in mammalian constitutive heterochromatin.5-甲基胞嘧啶定位于哺乳动物的组成型异染色质中。
Nature. 1974 Oct 18;251(5476):636-7. doi: 10.1038/251636a0.
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[Polymorphisms in human chromosomes--a new aid for affiliation cases (author's transl)].[人类染色体多态性——亲子鉴定案例的新辅助手段（作者译）]
Z Rechtsmed. 1974 Mar 29;74(1):17-23. doi: 10.1007/BF01869180.
10
Quinacrine, a chromosome stain specific for deoxyadenylate-deoxythymidylaterich regions in DNA.喹吖因，一种对DNA中富含脱氧腺苷酸-脱氧胸苷酸区域具有特异性的染色体染色剂。
Proc Natl Acad Sci U S A. 1972 Mar;69(3):629-32. doi: 10.1073/pnas.69.3.629.