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关于人类15号染色体的结构与多态性

On the structure and polymorphism of the human chromosome no. 15.

作者信息

Wachtler F, Musil R

出版信息

Hum Genet. 1980;56(1):115-8. doi: 10.1007/BF00281580.

Abstract

Chromosome preparations from 67 randomly selected healthy individuals were consecutively stained with silver, mithramycin, pentamidine-DAPI, and quinacrine mustard. In the short arm of the chromosome 15 up to six regions, which were highly polymorphic, apparently independently of each other, could be detected by the given methods. The frequency of occurrence of each individual polymorphic feature in the population investigated ranges from 70% to 87%. They appear randomly and independently of each other.

摘要

从67名随机挑选的健康个体中制备染色体标本,依次用银染、放线菌素D、喷他脒 - 二氨基苯基吲哚(DAPI)和喹吖因芥子气进行染色。在15号染色体短臂上,通过给定方法可检测到多达六个高度多态性的区域,这些区域显然彼此独立。在所研究的人群中,每个个体多态性特征的出现频率在70%至87%之间。它们随机出现且彼此独立。

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