Intensity heteromorphisms of human chromosome 15p by DA/DAPI technique.

We suggest that the short arms of human chromosome 15 (15p) exhibit intensity heteromorphisms by DA/DAPI technique. A method for classification of variable intensities is proposed. The different intensities can be classified into at least five classes. They are: negative, pale, medium, intense, and brilliant. Therefore we suggest that 15p is not always positive by DA/DAPI technique. The present findings reveal that the heteromorphism on 15p is far greater than previously thought.