Bigazzi M, Sardano G, Martino E, Vaudagna G, Ronga R, Pinchera A, Baschieri L
J Endocrinol Invest. 1980 Oct-Dec;3(4):439-40. doi: 10.1007/BF03349386.
Measurements of serum thyroxine binding globulin (TBG) by a ligand partitioning sandwich assay were performed in 173 healthy subjects between three months and 92 yr of age. Significant sex-related differences were observed in subjects aged 21 to 50 yr. In males, serum TBG declined progressively reaching a nadir in the fourth decade and then increased with advancing age. In contrast, no significant age-related variation was observed in females.
采用配体分配夹心分析法对173名年龄在3个月至92岁之间的健康受试者进行血清甲状腺素结合球蛋白（TBG）检测。在21至50岁的受试者中观察到显著的性别差异。在男性中，血清TBG逐渐下降，在第四个十年达到最低点，然后随着年龄的增长而增加。相比之下，在女性中未观察到与年龄相关的显著变化。
