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美西律制剂的抗心律失常作用及其对心肌收缩功能的影响

[Antiarrhythmic effect and influence on myocardial contractile function of the preparation, mexitil].

作者信息

Ol'binskaia L I, Iurina M S, Litvitskiĭ P F, Sandrikov V A

出版信息

Kardiologiia. 1980 Dec;20(12):10-3.

PMID:6162995
Abstract

Complex clinical instrumental examination of 30 patients with disorders of cardiac rhythm and experimental study on 49 albino rats with induced transitory coronary insufficiency of various duration which were then subjected to reperfusion showed that Mexitil is an effective anti-arrhythmic agent in the treatment of ventricular disorders of rhythm and that during long-term treatment wih it inotropic myocardial function diminishes insignificantly; treatment produced positive results in 73% of patients.

摘要

对30例心律失常患者进行了复杂的临床仪器检查,并对49只诱发了不同时长短暂性冠状动脉供血不足随后又进行再灌注的白化大鼠进行了实验研究,结果表明慢心律是治疗室性心律失常的一种有效抗心律失常药物,并且在长期使用该药治疗期间心肌收缩功能仅有轻微下降;73%的患者治疗取得了积极效果。

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