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Isolation and partial characterization of a low molecular weight trypsin inhibitor from human urine.

作者信息

Fex G, Grubb A, Loeffler C, Larsson J

出版信息

Biochim Biophys Acta. 1981 Feb 27;667(2):303-8. doi: 10.1016/0005-2795(81)90196-3.

DOI:10.1016/0005-2795(81)90196-3
PMID:6163474
Abstract

A low molecular weight glycoprotein which completely inhibited trypsin at a 1 : 1 molar ratio was isolated from human urine. It was generated from a precursor molecule which in turn derived from plasma inter-alpha-trypsin inhibitor. It had one polypeptide chain with a molecular weight of about 20 000 and a high content of half-cystine residues. Its amino-terminal amino-acid sequence was Val-Thr-Glu-Val-Thr-X-Leu-Glu-Asp-.

摘要

相似文献

1
Isolation and partial characterization of a low molecular weight trypsin inhibitor from human urine.
Biochim Biophys Acta. 1981 Feb 27;667(2):303-8. doi: 10.1016/0005-2795(81)90196-3.
2
Kunitz-type proteinase inhibitors derived by limited proteolysis of the inter-alpha-trypsin inhibitor, V. Attachments of carbohydrates in the human urinary trypsin inhibitor isolated by affinity chromatography.
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3
Kunitz-type proteinase inhibitors derived by limited proteolysis of the inter-alpha-trypsin inhibitor, IV. The amino acid sequence of the human urinary trypsin inhibitor isolated by affinity chromatography.
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Carbohydrate as covalent crosslink in human inter-alpha-trypsin inhibitor: a novel plasma protein structure.
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Purification and characterization of a tumor-associated trypsin inhibitor from the urine of a patient with ovarian cancer.从一名卵巢癌患者尿液中纯化并鉴定一种肿瘤相关胰蛋白酶抑制剂。
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Isolation of acid-resistant urinary trypsin inhibitors by high performance liquid chromatography and their characterization by N-terminal amino-acid sequence determination.通过高效液相色谱法分离耐酸尿胰蛋白酶抑制剂并通过N端氨基酸序列测定对其进行表征。
Hoppe Seylers Z Physiol Chem. 1984 Sep;365(9):1123-30. doi: 10.1515/bchm2.1984.365.2.1123.
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Human granulocyte elastase is inhibited by the urinary trypsin inhibitor.人粒细胞弹性蛋白酶受到尿胰蛋白酶抑制剂的抑制。
Hoppe Seylers Z Physiol Chem. 1982 Oct;363(10):1167-75. doi: 10.1515/bchm2.1982.363.2.1167.
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The inter-alpha-trypsin inhibitor.α-胰蛋白酶抑制因子间体
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The inter-alpha-trypsin inhibitor as precursor of the acid-stable proteinase inhibitors in human serum and urine.人血清和尿液中酸稳定蛋白酶抑制剂的前体——α-间胰蛋白酶抑制剂
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Isolation and characterization of an inter-alpha-trypsin inhibitor-IgG complex from human serum.从人血清中分离并鉴定一种α-胰蛋白酶抑制剂-IgG复合物
Biochim Biophys Acta. 1983 Jan 12;742(1):206-14. doi: 10.1016/0167-4838(83)90378-3.

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Identification of a specific interleukin 1 inhibitor in the urine of febrile patients.在发热患者尿液中鉴定出一种特异性白细胞介素1抑制剂。
J Exp Med. 1984 Jan 1;159(1):126-36. doi: 10.1084/jem.159.1.126.
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The amino acid factor in stone formers' and normal urines.结石患者尿液和正常尿液中的氨基酸因素。
Urol Res. 1986;14(6):295-8. doi: 10.1007/BF00262378.