Palladini G, Margotta V, Medolago-Albani L, Hernandez M C, Carolei A, de Michele T
Cell Tissue Res. 1981;215(2):271-9. doi: 10.1007/BF00239114.
Photosensitization phenomena may be induced in planarias by eosin and hematoporphyrin, and as a result, dopamine agonistic behavior ("screw-like hyperkinesia") is set up in the animal. Histochemical, ultrastructural and pharmacological investigations have shown that this hyperkinesia is of post-synaptic origin in eosin photosensitization, and of pre-synaptic origin in hematoporphyrin photosensitization. The authors suggest an hypothesis to explain the different activity of the two photosensitizers, and discuss the validity of the experiment with regard to human porphyria.
曙红和血卟啉可在涡虫中诱发光敏化现象，结果该动物会出现多巴胺激动行为（“螺旋状运动亢进”）。组织化学、超微结构和药理学研究表明，这种运动亢进在曙红光敏化中起源于突触后，而在血卟啉光敏化中起源于突触前。作者提出了一个假说来解释这两种光敏剂的不同活性，并讨论了该实验对于人类卟啉症的有效性。
