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胎儿与母体血液灌注;猪胎儿导管插入术后可能出现的后遗症。

Fetal perfusion with maternal blood; a possible sequel to fetal catheterization in the pig.

作者信息

Randall G C, Nielsen K

出版信息

J Dev Physiol. 1980 Aug;2(4):249-56.

PMID:6163811
Abstract

Plasma gamma-globulin concentrations were increased in three catheterized pig fetuses in which the packed red cell volume rose rapidly after surgery, but were not increased in one fetus in which the packed cell volume remained normal. The increases in packed cell volume and gamma-globulin concentration were closely correlated. The source of the gamma-globulin was investigated in one sow with catheterized fetuses. Maternal proteins, identified by [125I]-labelling and gel diffusion, crossed to the circulation of the one catheterized fetus with an elevated packed cell volume but not to the other, in which packed cell volume remained normal, nor to two unoperated fetuses. The results suggest that vascular anastmosis between fetal and maternal circulations is a possible sequel to cannulation in this species.

摘要

在三只接受插管的猪胎儿中,血浆γ-球蛋白浓度升高,这些胎儿术后红细胞压积迅速上升,但在一只红细胞压积保持正常的胎儿中,血浆γ-球蛋白浓度并未升高。红细胞压积和γ-球蛋白浓度的升高密切相关。对一只怀有接受插管胎儿的母猪进行了γ-球蛋白来源的研究。通过[125I]标记和凝胶扩散鉴定的母体蛋白,进入了一只红细胞压积升高的接受插管胎儿的循环,但未进入另一只红细胞压积保持正常的接受插管胎儿以及两只未手术胎儿的循环。结果表明,在该物种中,胎儿与母体循环之间的血管吻合可能是插管后的一个后遗症。

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