Wolbarsht M L, Landers M B, Stefansson E
Ophthalmic Surg. 1981 Feb;12(2):104-7.
The evidence in support of the theory that retinal vascular stretching leads to leakage, formation of microaneurysms, and neovascularization is reviewed. The efficacy of photocoagulation and vitrectomy in controlling retinal microangiopathy accompanying diabetes is shown to depend upon reduction of the vascular dilatation. It is possible that the vascular dilatation in diabetes results from high blood glucose levels increasing oxygen consumption in the inner retina, with a resulting vascular dilatation to supply increased oxygen to the retina. This retinal vascular dilatation is the initial cause of the vascular pathology in diabetes.
本文回顾了支持视网膜血管拉伸导致渗漏、微动脉瘤形成和新生血管形成这一理论的证据。光凝和玻璃体切除术在控制糖尿病伴发的视网膜微血管病变方面的疗效显示取决于血管扩张的减轻。糖尿病中的血管扩张可能是由于高血糖水平增加了视网膜内层的氧消耗，从而导致血管扩张以向视网膜供应更多的氧。这种视网膜血管扩张是糖尿病血管病变的初始原因。
