Buck P, Mickelson M R, Bonfiglio M
Clin Orthop Relat Res. 1981 May(156):211-5.
Thirty-three patients with synovial sarcoma were studied with respect to age, sex, site, clinical presentation, pathologic findings, and primary surgical treatment. Seventy percent of the patients were in the first three decades of life, and there was a 2:1 male predominance; the overall survival rate was 36%. There was a high local recurrence rate (64%) after simple local excision, and poor survival (27%). While wide local resection gave the best results (50% survival), it also carried a risk of high recurrence. Patients treated by amputation had a 42% survival rate. Thus, it can be concluded that adequate surgical treatment improved survival and reduced the recurrence rates. The lungs were the most common metastatic site, but lymph node metastasis occurred in 27% of the patients, often after tumor recurrence. Favorable prognostic factors included youth (patients younger than 20) and biphasic or epitheloid histologic types.
对33例滑膜肉瘤患者进行了年龄、性别、部位、临床表现、病理结果及初次手术治疗等方面的研究。70%的患者年龄在人生的头三十年，男性占比为2:1；总体生存率为36%。单纯局部切除后的局部复发率较高（64%），生存率较差（27%）。而广泛局部切除效果最佳（生存率50%），但也有高复发风险。接受截肢治疗的患者生存率为42%。因此，可以得出结论，充分的手术治疗可提高生存率并降低复发率。肺是最常见的转移部位，但27%的患者发生淋巴结转移，且多在肿瘤复发后。有利的预后因素包括年轻（20岁以下患者）以及双相或上皮样组织学类型。
