Selective enhancement of 5-fluorouridine uptake and action in rat hepatomas in vivo following pretreatment with D-galactosamine and 6-azauridine or N-(phosphonacetyl)-L-aspartate.

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作者信息

Anukarahanonta T, Holstege A, Keppler D O

出版信息

Eur J Cancer (1965). 1980 Sep;16(9):1171-80. doi: 10.1016/0014-2964(80)90176-0.

DOI:10.1016/0014-2964(80)90176-0

PMID:6164559

Abstract

摘要

相似文献

Selective enhancement of 5-fluorouridine uptake and action in rat hepatomas in vivo following pretreatment with D-galactosamine and 6-azauridine or N-(phosphonacetyl)-L-aspartate.

Eur J Cancer (1965). 1980 Sep;16(9):1171-80. doi: 10.1016/0014-2964(80)90176-0.

Serum uridine levels in patients receiving N-(phosphonacetyl)-L-aspartate.接受 N-(膦酰基乙酰基)-L-天冬氨酸治疗的患者的血清尿苷水平。

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Effect of inhibitors of the de novo pyrimidine biosynthetic pathway on serum uridine levels in mice.从头嘧啶生物合成途径抑制剂对小鼠血清尿苷水平的影响。

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Improved therapeutic index with sequential N-phosphonacetyl-L-aspartate plus high-dose methotrexate plus high-dose 5-fluorouracil and appropriate rescue.通过序贯使用N-磷乙酰-L-天冬氨酸、大剂量甲氨蝶呤和大剂量5-氟尿嘧啶并进行适当解救，治疗指数得到改善。

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Phase II evaluation of N-(phosphonacetyl-L-aspartic acid (PALA) in patients with advanced colorectal carcinoma.N-（膦酰乙酰-L-天冬氨酸）（PALA）用于晚期结直肠癌患者的II期评估。

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Phase II evaluation of N-(phosphonacetyl)-L-aspartic acid (PALA) in patients with non-small cell carcinoma of the lung.N-（膦酰基乙酰基）-L-天冬氨酸（PALA）用于非小细胞肺癌患者的II期评估。

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Effects of N-(phosphonacetyl)-L-aspartate on murine tumors and normal tissues in vivo and in vitro and the relationship of sensitivity to rate of proliferation and level of aspartate transcarbamylase.N-（膦酰基乙酰基）-L-天冬氨酸对小鼠肿瘤及正常组织的体内外作用以及敏感性与增殖速率和天冬氨酸转氨甲酰酶水平的关系

Cancer Res. 1978 Feb;38(2):371-8.

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