Asher R, Hunt S, Hamilton A M, Townsend C, Blach R K, Khoury D, Kohner E M, Morris D V
Int Ophthalmol. 1981 Mar;3(2):79-85. doi: 10.1007/BF00133418.
The effects of treatment by argon laser and xenon arc photocoagulation in 165 diabetic patients with optic disc new vessel formation have been studied retrospectively. Visual acuity and degree of new vessel formation have been assessed over a period of between six months and seven years of follow-up (mean 23 months). Visual acuity improved in 36% of treated eyes and remained unchanged in 34%. Improvement was most marked in those with initially poor acuity (less than 6/36). There was no association between improvement in visual acuity and regression of disc vessels, the latter occurring in 79% of treated eyes. Only 6% of eyes became blind during the period of follow-up, principally as a result of vitreous haemorrhage and retinal detachment. There was no difference between the results produced by the use of separate or combined argon laser and xenon arc photocoagulation on the regression of disc new vessels. However, our results suggest that argon laser treatment was more effective than xenon arc photocoagulation in improving visual acuity. These findings suggest that either form of treatment or a combination offers considerable benefit in the management of proliferative diabetic retinopathy, even when very severe at presentation.
对165例患有视盘新生血管形成的糖尿病患者进行氩激光和氙弧光凝治疗的效果进行了回顾性研究。在6个月至7年的随访期(平均23个月)内评估了视力和新生血管形成程度。36%的治疗眼视力提高,34%保持不变。视力最初较差(低于6/36)的患者改善最为明显。视力改善与视盘血管消退之间无关联,后者出现在79%的治疗眼中。随访期间仅6%的眼失明,主要是由于玻璃体出血和视网膜脱离。单独或联合使用氩激光和氙弧光凝对视盘新生血管消退产生的结果无差异。然而,我们的结果表明,氩激光治疗在提高视力方面比氙弧光凝更有效。这些发现表明,即使在就诊时病情非常严重,任何一种治疗方式或联合治疗在增殖性糖尿病视网膜病变的管理中都能带来相当大的益处。