Crane J, Anderson B, Marshall R, Harvey P
J Reprod Med. 1981 Mar;26(3):113-8.
Little knowledge exists concerning long-term sequelae in children born of pregnancies complicated by chronic uteroplacental insufficiency. This follow-up study evaluates 12 children with positive contraction stress tests (CSTs) 5.5 months to 4.75 years following birth. Subsequent physical growth was uniformly normal in the four infants classified as appropriate for gestational age at birth; however, continued postnatal growth deficiency was present in 50% of the eight infants who suffered from intrauterine growth retardation. No major neurologic abnormalities were detected, and 10 of the 12 displayed normal mental and motor function, as determined by the Denver Developmental Screening Test, Bayley Scales of Infant Development and Wechsler Preschool and Primary Scale of Intelligence. Two of the 12 infants were depressed at birth and had serious neonatal complications. These were the only two children who scored poorly on the Bayley test. Although no conclusions regarding minimal brain dysfunction can be made, the majority of infants with positive CSTs demonstrate grossly normal neurologic and psychologic development.
关于患有慢性子宫胎盘功能不全的妊娠所生孩子的长期后遗症，目前了解甚少。这项随访研究评估了12名出生后5.5个月至4.75年期间宫缩应激试验（CST）呈阳性的儿童。在出生时分类为适于胎龄儿的4名婴儿中，随后的身体生长均正常；然而，在8名患有宫内生长迟缓的婴儿中，50%存在出生后持续生长不足。未检测到重大神经异常，根据丹佛发育筛查测试、贝利婴儿发育量表和韦氏学前及初小儿童智能量表测定，12名儿童中有10名表现出正常的智力和运动功能。12名婴儿中有2名出生时情况不佳，并有严重的新生儿并发症。这是仅有的两名在贝利测试中得分较低的儿童。虽然无法得出关于最小脑功能障碍的结论，但大多数CST呈阳性的婴儿表现出总体正常的神经和心理发育。
