Eskay R L, Furness J F, Long R T
Science. 1981 May 29;212(4498):1049-50. doi: 10.1126/science.6165081.
Immunoreactive substance P is present in the bullfrog retina, possibly in two types of stratified amacrine cells, with their somas in the inner nuclear layer and their neuronal processes entering the inner plexiform layer and ramifying in sublayers 3 or 4 (or both). Occasionally, polygonal somas positive for substance P were found in the ganglion cell layer. Approximately 75 percent of the cell bodies positive for substance P and 65 percent of the radioimmunoassayable substance P were found in the superior half of the frog retina. On the basis of high-performance liquid chromatography, the immunoreactive substance P in the neural retina of the rat, monkey, or chick is similar to synthetic substance P, whereas this is not true of the immunoreactive substance P in the bullfrog or carp retina.
免疫反应性P物质存在于牛蛙视网膜中，可能存在于两种类型的分层无长突细胞中，它们的胞体位于内核层，其神经突进入内网状层并在第3或第4亚层（或两者）中分支。偶尔，在神经节细胞层中发现对P物质呈阳性的多边形胞体。在蛙视网膜的上半部分发现了约75%对P物质呈阳性的细胞体和65%可进行放射免疫测定的P物质。基于高效液相色谱法，大鼠、猴子或鸡的神经视网膜中的免疫反应性P物质与合成P物质相似，而牛蛙或鲤鱼视网膜中的免疫反应性P物质则并非如此。
