Thomas W R, Watkins M C, Cox K O, Asherson G L
J Immunol. 1981 Jul;127(1):217-20.
T cells from mice injected with picryl sulfonic acid (PSA) can inhibit the anti-trinitrophenyl (TNP) antibody responses of mice produced after skin painting with picryl chloride (PCl). This had unusual specificity because the cells could inhibit IgG PFC responses in draining lymph nodes by 90% without affecting anti-TNP IgE responses as measured by heterologous adoptive cutaneous anaphylaxis. Although showing specificity for the class of antibody, the suppressors did inhibit IgG antibody responses to another sensitizer, oxazolone, although to a lesser degree. Responses to TNP-KLH, however, were unaffected.
注射了苦味酸磺酸（PSA）的小鼠的T细胞可以抑制在用苦味酸氯（PCl）进行皮肤涂抹后产生的小鼠的抗三硝基苯基（TNP）抗体反应。这具有不寻常的特异性，因为这些细胞可以抑制引流淋巴结中90%的IgG PFC反应，而不影响通过异种过继性皮肤过敏反应测量的抗TNP IgE反应。尽管对抗体类别表现出特异性，但这些抑制细胞确实能抑制对另一种致敏剂恶唑酮的IgG抗体反应，尽管程度较小。然而，对TNP-KLH的反应不受影响。
