猿猴病毒40大T抗原与D2杂交T抗原之间的免疫交叉反应性。
Immunological cross-reactivity between simian virus 40 large T antigen and D2 hybrid T antigen.
作者信息
Baumann E A, Stedman D, Raptis L, Fuks A, Hand R
出版信息
J Virol. 1981 Jun;38(3):1090-4. doi: 10.1128/JVI.38.3.1090-1094.1981.
Abstract
A specific antiserum was raised in rabbits against D2 hybrid T antigen that had been purified from HeLa cells infected with the adenovirus/simian virus 40 hybrid, Ad2(+)D2. The specificity of this serum was compared with that of a conventional hamster antiserum against simian virus 40-induced tumors by immunoprecipitation and by a new radioimmune assay that can detect nanogram quantities of D2 hybrid T antigen.
摘要
用从感染腺病毒/猴病毒40杂种Ad2(+)D2的HeLa细胞中纯化的D2杂种T抗原，在兔中制备了一种特异性抗血清。通过免疫沉淀和一种能检测纳克量D2杂种T抗原的新型放射免疫测定法，将该血清的特异性与针对猴病毒40诱导肿瘤的传统仓鼠抗血清的特异性进行了比较。
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