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[降钙素治疗前列腺癌溶骨性转移所致疼痛症状的结果]

[Results of calcitonin therapy of the painful symptoms caused by osteolytic metastases of prostatic carcinoma].

作者信息

Fabris P, Strada G, Tonazzi G, Rossi A, Franchini V, Scardino E

出版信息

Chir Ital. 1980 Dec;32(6):1740-4.

PMID:6166404
Abstract

Albeit within the limits imposed on us by the restricted number of cases, we can state that--in the present state of research--calcitonin constitutes a useful complement in treatment of osteolytic metastasis induced by carcinoma of the prostate. Is utilisation is justified by the effects observed: on the one hand, osteogenesis as a factor protecting against the aggressivity of the tumoural cells, and on the other the considerable antalgic strength allied with improvement in the calcium, phosphorus and phosphatase values. For some time we have replaced pig calcitonin with salmon calcitonin: the comparative results with this second product will be the subject of a subsequent paper.

摘要

尽管我们所研究的病例数量有限,但我们可以指出,在目前的研究状况下,降钙素是治疗前列腺癌所致溶骨性转移的一种有用补充药物。其应用的合理性基于所观察到的效果:一方面,成骨作用作为一种抵御肿瘤细胞侵袭性的因素;另一方面,其具有显著的止痛效力,同时伴有钙、磷及磷酸酶值的改善。一段时间以来,我们已用鲑鱼降钙素取代了猪降钙素:关于第二种产品的对比结果将是后续一篇论文的主题。

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