Lohmann H, Buck-Gramcko D
Handchirurgie. 1980;12(1-2):89-92.
Treatment with DEBRISORB, a new topical agent formed by three dimensional network of dextran polymers in porous hydrophilic beads, was used in 26 cases of infected wounds in the hand. These were of traumatic and postoperative origin, often with remaining necrotic areas and in a few cases with a considerable oedema. The special effect of DEBRISORB was in absorbing the exudate and in reducing the inflammation and swelling of the discharging wounds. Within a few days secretion was diminished and healthy granulation tissue appeared. For covering the defects we employed local transposition flaps, direct flaps and split-skin grafts without complications. Local treatment with DEBRISORB is an effective method to clean infected wounds, to reduce inflammation and oedema, and is useful as treatment before grafting.
使用DEBRISORB进行治疗,它是一种由多孔亲水性微珠中的葡聚糖聚合物三维网络构成的新型局部用药,应用于26例手部感染伤口。这些伤口源于创伤和术后,常伴有残留坏死区域,少数病例有相当程度的水肿。DEBRISORB的特殊作用在于吸收渗出物,减轻引流伤口的炎症和肿胀。数天内分泌物减少,健康的肉芽组织出现。我们采用局部转移皮瓣、直接皮瓣和分层皮片移植来覆盖缺损,未出现并发症。用DEBRISORB进行局部治疗是清洁感染伤口、减轻炎症和水肿的有效方法,并且在移植前的治疗中很有用。