[抗生素作为原核生物蛋白质生物合成的抑制剂：作用及耐药机制（作者译）]
[Antibiotics as inhibitors of the prokaryotic protein biosynthesis: action and resistance mechanisms (author's transl)].
作者信息
Nierhaus K H
出版信息
Immun Infekt. 1981;9(3):88-98.
PMID:6166542
Abstract
Most of the known antibiotics interfere with the translational apparatus due to the extraordinary complexity of the translational organelle, the ribosome. After a short survey on structure and function of the ribosome the action of some antibiotics is explained and integrated in an extended scheme of ribosomal functions. Furthermore, various resistance strategies of the translational apparatus against the antibiotics are described.
摘要
由于翻译细胞器核糖体极其复杂，大多数已知抗生素会干扰翻译装置。在对核糖体的结构和功能进行简要概述后，解释了一些抗生素的作用，并将其纳入核糖体功能的扩展框架中。此外，还描述了翻译装置对抗生素的各种抗性策略。
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