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口服芳香维甲酸(RO 10-9359)治疗期间的维生素A转运复合物

Vitamin A transport complex during treatment with an oral aromatic retinoid (RO 10-9359).

作者信息

Lauharanta J

出版信息

Acta Derm Venereol. 1981;61(3):264-7.

PMID:6167115
Abstract

No significant changes were noted in the serum levels or molar ratios of vitamin A, retinol-binding protein (RBP) and prealbumin even during long-term (up to 15 months) treatment with RO 10-9359 in 19 patients with normal renal function. Nor did any significant alteration occur in the highly significant correlations between vitamin A and RBP, and between RBP and prealbumin. In 3 patients with slightly elevated serum creatinine, some tendency towards an elevation of vitamin A and RBP levels was seen.

摘要

在19名肾功能正常的患者中,即使接受长达15个月的RO 10-9359治疗,也未发现维生素A、视黄醇结合蛋白(RBP)和前白蛋白的血清水平或摩尔比有显著变化。维生素A与RBP之间以及RBP与前白蛋白之间的高度显著相关性也未发生任何显著改变。在3名血清肌酐略有升高的患者中,观察到维生素A和RBP水平有升高的趋势。

相似文献

1
Vitamin A transport complex during treatment with an oral aromatic retinoid (RO 10-9359).口服芳香维甲酸(RO 10-9359)治疗期间的维生素A转运复合物
Acta Derm Venereol. 1981;61(3):264-7.
2
[Serum content of vitamin A binding proteins (prealbumin and retinol binding proteins) in normal and pathological conditions].[正常及病理状态下维生素A结合蛋白(前白蛋白和视黄醇结合蛋白)的血清含量]
Boll Soc Ital Biol Sper. 1983 Jul 30;59(7):1041-7.
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Int J Vitam Nutr Res. 1988;58(3):281-3.
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[Metabolism of vitamin A in Forestier-Rotès-Quérol hyperostosis].
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Serum retinol, retinol-binding protein, and transthyretin in children receiving dialysis.血清视黄醇、视黄醇结合蛋白和转甲状腺素蛋白在接受透析的儿童中的变化。
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The molar ratio of serum retinol-binding protein (RBP) to transthyretin (TTR) is not useful to assess vitamin A status during infection in hospitalised children.血清视黄醇结合蛋白(RBP)与转甲状腺素蛋白(TTR)的摩尔比对于评估住院儿童感染期间的维生素A状况并无用处。
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[Transport proteins for vitamin A. Retinol binding protein (RBP) and prealbumin (PA) in the serum of patients with carcinomas of the mouth].[维生素A的转运蛋白。口腔癌患者血清中的视黄醇结合蛋白(RBP)和前白蛋白(PA)]
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引用本文的文献

1
Etretinate. A review of its pharmacological properties and therapeutic efficacy in psoriasis and other skin disorders.依曲替酯。对其药理特性及在银屑病和其他皮肤病中的治疗效果的综述。
Drugs. 1983 Jul;26(1):9-43. doi: 10.2165/00003495-198326010-00002.
2
Psoriasis and vitamin A. Plasma transport and skin content of retinol, dehydroretinol and carotenoids in adult patients versus healthy controls.银屑病与维生素A。成年患者与健康对照者中视黄醇、脱氢视黄醇和类胡萝卜素的血浆转运及皮肤含量
Arch Dermatol Res. 1985;278(1):17-24. doi: 10.1007/BF00412490.
3
Clinical pharmacokinetics of the retinoids.
类视黄醇的临床药代动力学。
Clin Pharmacokinet. 1985 Jan-Feb;10(1):38-62. doi: 10.2165/00003088-198510010-00002.