Mohanachari V, Neeraja P, Indira K, Swami K S
Arch Int Physiol Biochim. 1981 May;89(2):97-100. doi: 10.3109/13813458109073988.
Substrate kinetics of arginase were investigated in normal and sciatectomized gastrocnemius muscle of frog. Sciatectomized muscle arginase showed 47% elevation in V while Km showed no change. Sciatectomic activation of muscle arginase accounted for the stepped up urea levels which may be of significant use in combating ammonia toxicity and maintaining chemohomeostasis.
在青蛙正常和坐骨神经切除的腓肠肌中研究了精氨酸酶的底物动力学。坐骨神经切除的肌肉精氨酸酶的V升高了47%,而Km没有变化。肌肉精氨酸酶的坐骨神经切除激活导致尿素水平升高,这可能在对抗氨毒性和维持化学稳态方面具有重要作用。