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坐骨神经切除蟾蜍腓肠肌某些脱氢酶谱的改变——苹果酸引起的代谢变化

Alterations in some dehydrogenase profiles of sciatectomized toad gastrocnemius muscle-metabolic modifications by malate.

作者信息

Prasad G V, Neeraja P, Swamy K S, Rajendra W, Indira K

出版信息

Indian J Physiol Pharmacol. 1984 Jul-Sep;28(3):227-30.

PMID:6519766
Abstract

Sciatectomized toad gastrocnemius has shown a progressive loss in lactate (LDH), succinate (SDH) and malate (MDH) dehydrogenase activities and elevation of glutamate dehydrogenase (GDH) activity during post-neurectemic days. The possible role of malate in the restoration of metabolic homeostasis in denervated muscle is discussed.

摘要

坐骨神经切除的蟾蜍腓肠肌在神经切除后的数天内,已显示出乳酸脱氢酶(LDH)、琥珀酸脱氢酶(SDH)和苹果酸脱氢酶(MDH)活性逐渐丧失,以及谷氨酸脱氢酶(GDH)活性升高。本文讨论了苹果酸在失神经肌肉代谢稳态恢复中的可能作用。

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