Ehrlichman R J, Kaufman S L, Siegelman S S, Trump D L, Walsh P C
J Urol. 1981 Aug;126(2):179-81. doi: 10.1016/s0022-5347(17)54434-1.
The usefulness of computerized tomography, lymphangiography and tumor markers has been examined in 20 consecutive patients with pathologic stage I or II nonseminomatous testicular tumors. Computerized tomography had a false negative rate of 40 per cent, a false positive rate of 50 per cent and an over-all accuracy of 69 per cent. Lymphangiography had a false negative rate of 42 per cent, a false positive rate of 0 and an over-all accuracy of 69 per cent. The combination of computerized tomography and lymphangiography did not significantly improve the diagnostic accuracy of either technique alone. Furthermore, because tumor markers usually were elevated in the presence of bulky metastatic disease that was detected easily by either computerized tomography or lymphangiography, they did not add measurably to the sensitivity of either computerized tomography or lymphangiography in the diagnosis of retroperitoneal lymph node metastases. Consequently, retroperitoneal lymphadenectomy remains the only reliable means for accurate staging of patients with nonseminomatous testicular tumors.
对连续20例病理分期为I期或II期的非精原细胞瘤性睾丸肿瘤患者进行了计算机断层扫描、淋巴管造影和肿瘤标志物的效用研究。计算机断层扫描的假阴性率为40%，假阳性率为50%，总体准确率为69%。淋巴管造影的假阴性率为42%，假阳性率为0，总体准确率为69%。计算机断层扫描和淋巴管造影联合使用并没有显著提高单独使用这两种技术的诊断准确性。此外，由于在存在大量转移性疾病时肿瘤标志物通常会升高，而这些疾病通过计算机断层扫描或淋巴管造影很容易检测到，因此它们并没有显著提高计算机断层扫描或淋巴管造影在诊断腹膜后淋巴结转移中的敏感性。因此，腹膜后淋巴结清扫术仍然是准确分期非精原细胞瘤性睾丸肿瘤患者的唯一可靠方法。
