Evermann J F, Krakowka S, McKeirnan A J, Baumgärtner W
Arch Virol. 1981;68(3-4):165-72. doi: 10.1007/BF01314569.
An isolate of canine parainfluenza (CPI) virus from the cerebrospinal fluid of a dog with neurological dysfunction was characterized in vitro in comparison to a prototype strain of CPI virus, D008. The virus, designated 78-238 was found to be antigenically related to CPI virus (Manhatten strain) and simian virus 5 (SV5), but not to mumps virus (Enders strain). Ultrastructural observation of gradient-purified 78-238 virus revealed enveloped pleomorphic virions with helical nucleocapsid symmetry. Preliminary pathological studies indicated that 78-238 virus was encephalitogenic for gnotobiotic dogs when inoculated by the intracerebral route.
从一只患有神经功能障碍的犬的脑脊液中分离出一株犬副流感（CPI）病毒，并与CPI病毒原型株D008进行了体外特性比较。该病毒命名为78 - 238，发现其与CPI病毒（曼哈顿株）和猴病毒5（SV5）存在抗原相关性，但与腮腺炎病毒（恩德斯株）无抗原相关性。对梯度纯化的78 - 238病毒进行超微结构观察，发现其为具有螺旋核衣壳对称性的包膜多形性病毒粒子。初步病理学研究表明，78 - 238病毒经脑内接种时对无菌犬具有致脑炎作用。
