Beletskaia L V, Vul'fovich Iu V, Gnezditskaia E V, Goncharova S A
Biull Eksp Biol Med. 1981 Jun;91(6):704-6.
Indirect immunofluorescence has shown a similarity between the antigen components of group A streptococcus L-forms and human thymus myoid cells. An analogous antigen (or antigens) is present in the cytoplasmic membrane of human myocardial cell fibers. The depletion of antiserum to the streptococcal L-forms both by the culture of L-forms grown in meat or casein media and by the homogenate of the cardiac muscle leads to the inhibition of immunofluorescence. The depletion of serum by the homogenate of other tissues (liver) or by L-form culture does not virtually affect the immunofluorescence intensity. According to the authors' opinion, the similarity of antigens of group A streptococcus L-forms to the antigenic components of organ tissues is likely to be responsible for long-term persistence of the microorganisms under consideration and to favour, in some cases, the occurrence of autoantibodies. The latter circumstance might lead to pathological changes in organs containing cross-reacting antigens.
间接免疫荧光显示A组链球菌L型的抗原成分与人类胸腺肌样细胞之间存在相似性。在人类心肌细胞纤维的细胞质膜中存在一种类似的抗原（或多种抗原）。用在肉或酪蛋白培养基中生长的L型培养物以及心肌匀浆处理抗链球菌L型血清，会导致免疫荧光受到抑制。用其他组织（肝脏）的匀浆或L型培养物处理血清，实际上并不影响免疫荧光强度。根据作者的观点，A组链球菌L型的抗原与器官组织的抗原成分相似，这可能是所研究的微生物长期持续存在的原因，并且在某些情况下有利于自身抗体的产生。后一种情况可能导致含有交叉反应抗原的器官发生病理变化。
