Nadji M, Tabei S Z, Castro A, Chu T M, Murphy G P, Wang M C, Morales A R
Cancer. 1981 Sep 1;48(5):1229-32. doi: 10.1002/1097-0142(19810901)48:5<1229::aid-cncr2820480529>3.0.co;2-l.
Antiserum to a human prostate-specific antigen was raised in a rabbit and utilized by immunoperoxidase staining to evaluate its potential value as a diagnostic histologic marker for tumors of prostatic origin. All primary and metastatic prostatic malignancies reacted positively, whereas nonprostatic neoplasms did not stain with this procedure. This is the first immunohistochemical marker for prostate gland epithelium which does not represent prostatic acid phosphatase.
用人前列腺特异性抗原在兔体内制备抗血清，并通过免疫过氧化物酶染色来评估其作为前列腺源性肿瘤诊断组织学标志物的潜在价值。所有原发性和转移性前列腺恶性肿瘤均呈阳性反应，而非前列腺肿瘤在此检测方法下不着色。这是第一种不代表前列腺酸性磷酸酶的前列腺腺上皮免疫组化标志物。
