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由口腔拟杆菌、具核梭杆菌和小韦荣球菌的脂多糖诱导大鼠腹膜肥大细胞产生的补体依赖性组胺释放。

Complement-dependent histamine release from rat peritoneal mast cells, induced by lipopolysaccharides from Bacteroides oralis, Fusobacterium nucleatum and Veillonella parvula.

作者信息

Nygren H, Dahlén G

出版信息

J Oral Pathol. 1981 Apr;10(2):87-94. doi: 10.1111/j.1600-0714.1981.tb01253.x.

DOI:10.1111/j.1600-0714.1981.tb01253.x
PMID:6168752
Abstract

The capacity of phenol/water extracted lipopolysaccharides (LPS) from Bacteroides, Fusobacterium and Veillonella to induce histamine release from rat peritoneal mast cells has been evaluated by means of a bioassay using atropinized guinea pig ileum and a fluorescence assay. Histamine release was found to be completely complement dependent. It was also found that LPS of Veillonella have the greatest capacity to induce histamine release and Bacteroides have the weakest.

摘要

已通过使用阿托品化豚鼠回肠的生物测定法和荧光测定法，评估了从拟杆菌属、梭杆菌属和韦荣球菌属中提取的苯酚/水脂多糖（LPS）诱导大鼠腹膜肥大细胞释放组胺的能力。发现组胺释放完全依赖补体。还发现韦荣球菌属的LPS诱导组胺释放的能力最强，而拟杆菌属的最弱。

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