Gilinskii M A, Dubrovina N I
Neurosci Behav Physiol. 1977 Jan-Mar;8(1):49-54. doi: 10.1007/BF01153604.
Commissural evoked potentials (EP) in hippocampal area CA1 were investigated during microiontophoretic application of sodium glutamate (SG) in experiments on unanesthetized rats immobilized with diplacin. EP were recorded by the central barrel of a five-barreled microiontophoretic microelectrode before and during application of SG. The effect of SG in the region of EP reversal was characterized by depression of the initial positive phase of the response and an increase in negativity. In the radial layer SG caused a substantial increase in the commissural response recorded at a depth. At a distance of 100 mu from the tip of the iontophoretic pipet no changes in EP were found. An increase in the intensity of transhippocampal stimulation was accompanied by a marked increase in the amplitude and a change in shape of the individual phases of EP and it abolished the effect of the microiontophoretically applied SG. During paired stimulation with an interval of 20--200 msec different effects of SG on the testing response were recorded depending on the length of the interval.
在用双醋酚汀固定的未麻醉大鼠实验中，在微量离子电泳施加谷氨酸钠（SG）期间，研究了海马CA1区的连合诱发电位（EP）。在施加SG之前和期间，通过五管微量离子电泳微电极的中央管记录EP。SG在EP反转区域的作用表现为反应初始正相的抑制和负性增加。在放射层，SG导致在一定深度记录的连合反应大幅增加。在距离子电泳移液管尖端100微米处，未发现EP有变化。海马跨区刺激强度的增加伴随着EP各相振幅的显著增加和形状的改变，并且消除了微量离子电泳施加的SG的作用。在间隔为20 - 200毫秒的配对刺激期间，根据间隔长度记录到SG对测试反应的不同影响。
