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微离子电渗法应用乙酰胆碱对视觉皮层对直接皮层刺激诱发活动的影响。

Effect of microiontophoretic application of acetylcholine on visual cortical evoked activity to direct cortical stimulation.

作者信息

Perkhurova V D, Zarkeshev E G

出版信息

Neurosci Behav Physiol. 1977 Jan-Mar;8(1):55-60. doi: 10.1007/BF01153605.

DOI:10.1007/BF01153605
PMID:616892
Abstract

Responses of visual cortical neurons (area 17) to direct cortical stimulation of visual areas 18 and 19 were investigated in acute experiments on adult unanesthetized cats, immobilized with diplacin, under local anesthesia, after microiontophoretic application of acetylcholine. Selectivity of the action of acetylcholine on the individual components of the unit responses to direct cortical stimulation was established. The role of acetylcholine as mediator of information in the mechanisms of transcortical interneuronal interaction within the visual system is discussed.

摘要

在成年未麻醉猫的急性实验中,用双丙烯酰(diplacin)使其固定,在局部麻醉下,于微量离子电泳施加乙酰胆碱后,研究了视觉皮层神经元(17区)对视觉18区和19区皮层直接刺激的反应。确定了乙酰胆碱对单位对皮层直接刺激反应的各个成分作用的选择性。讨论了乙酰胆碱作为信息介质在视觉系统内跨皮层神经元间相互作用机制中的作用。

相似文献

1
Effect of microiontophoretic application of acetylcholine on visual cortical evoked activity to direct cortical stimulation.微离子电渗法应用乙酰胆碱对视觉皮层对直接皮层刺激诱发活动的影响。
Neurosci Behav Physiol. 1977 Jan-Mar;8(1):55-60. doi: 10.1007/BF01153605.
2
[The effect of microiontophoretic administration of acetylcholine on evoked activity of visual cortex neurons subjected to direct cortical stimulation].[微离子电渗法给予乙酰胆碱对接受直接皮层刺激的视皮层神经元诱发电活动的影响]
Fiziol Zh SSSR Im I M Sechenova. 1976 Mar;62(3):342-8.
3
[Effect of serotonin on neuronal activity in the visual region of the cerebral cortex evoked by direct cortical stimulation].[血清素对大脑皮层直接刺激诱发的大脑皮层视觉区域神经元活动的影响]
Neirofiziologiia. 1977;9(2):198-201.
4
Acetylcholine sensitivity of partially deafferented cortex.部分去传入皮质的乙酰胆碱敏感性
Epilepsia. 1969 Sep;10(3):419.
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[Shifts in spatial synchronization of rabbit cortical potentials evoked by applying acetylcholine and amizil to the visual area].[应用乙酰胆碱和阿米齐尔于视觉区域诱发兔皮层电位的空间同步性变化]
Zh Vyssh Nerv Deiat Im I P Pavlova. 1987 Sep-Oct;37(5):843-9.
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Effects of deuterium oxide and galvanic vestibular stimulation on visual cortical cell function.氧化氘和前庭电刺激对视觉皮层细胞功能的影响。
J Neurophysiol. 1984 Mar;51(3):481-99. doi: 10.1152/jn.1984.51.3.481.
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A functional role of cholinergic innervation to neurons in the cat visual cortex.胆碱能神经支配对猫视觉皮层神经元的功能作用。
J Neurophysiol. 1987 Oct;58(4):765-80. doi: 10.1152/jn.1987.58.4.765.
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[Effect of microiontophoretic application of serotonin on the background impulse activity of visual cortex neurons in unanesthetized cats].[5-羟色胺微离子电泳对未麻醉猫视皮层神经元背景冲动活动的影响]
Zh Vyssh Nerv Deiat Im I P Pavlova. 1976 Nov-Dec;26(6):1276-81.
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[Neuronal mechanisms of sensory integration in the visual analyzer system].[视觉分析器系统中感觉整合的神经元机制]
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Acetylcholine-induced inhibition in the cat visual cortex is mediated by a GABAergic mechanism.乙酰胆碱在猫视觉皮层中引起的抑制作用是由一种γ-氨基丁酸能机制介导的。
Brain Res. 1989 May 22;487(2):335-42. doi: 10.1016/0006-8993(89)90837-8.

本文引用的文献

1
[On the structure and segmentation of the cortical center of vision in the cat].[关于猫视觉皮层中枢的结构与分区]
Arch Psychiatr Nervenkr Z Gesamte Neurol Psychiatr. 1962;203:212-34. doi: 10.1007/BF00352744.
2
Cortico-cortical connexions of the cat visual areas.猫视觉区域的皮质-皮质连接
J Anat. 1968 Mar;102(Pt 3):375-86.
3
[Evoked impulse activity in a neuronally isolated cortex].[神经元分离皮层中的诱发冲动活动]
Neirofiziologiia. 1971 May-Jun;3(3):236-44.
4
Pharmacological studies on a cholinergic inhibition in the cerebral cortex.大脑皮层胆碱能抑制作用的药理学研究
Brain Res. 1968 Sep;10(3):297-306. doi: 10.1016/0006-8993(68)90201-1.
5
Corticocortical fiber connections of the cat cerebrum. 3. The occipital region.
Brain Res. 1973 Mar 15;51:41-60. doi: 10.1016/0006-8993(73)90364-8.
6
Synaptic transmission in the brain.大脑中的突触传递。
Klin Wochenschr. 1971 May 1;49(9):519-23. doi: 10.1007/BF01487988.