Lisoprawski A, Blanc G, Glowinski J
Neurosci Lett. 1981 Aug 7;25(1):47-51. doi: 10.1016/0304-3940(81)90099-9.
Substance P levels were significantly decreased in the ventro-tegmental area and the interpeduncular nucleus of rats submitted for 20 min to electric foot-shocks. Substance P levels in the substantia nigra and in the prefrontal cortex were not affected. These results are discussed in light of the selective activation of the mesocortico-prefrontal dopaminergic neurons induced by this stress situation.
接受20分钟足部电击的大鼠，其腹侧被盖区和脚间核中的P物质水平显著降低。黑质和前额叶皮质中的P物质水平未受影响。根据这种应激情况诱导的中皮质-前额叶多巴胺能神经元的选择性激活对这些结果进行了讨论。
