Effect of the immunoneutralization of substance P in the cat substantia nigra on the release of dopamine from dendrites and terminals of dopaminergic neurons.

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作者信息

Cheramy A, Michelot R, Leviel V, Nieoullon A, Glowinski J, Kerdelhue B

出版信息

Brain Res. 1978 Oct 27;155(2):404-8. doi: 10.1016/0006-8993(78)91038-7.

DOI:10.1016/0006-8993(78)91038-7

PMID:688024

Abstract

摘要

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Effect of the immunoneutralization of substance P in the cat substantia nigra on the release of dopamine from dendrites and terminals of dopaminergic neurons.

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Intranigral application of substance P antagonists prevents the haloperidol-induced activation of striatal tyrosine hydroxylase.

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Organization and physiology of the substantia nigra.

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The selective NK3 receptor agonist senktide excites a subpopulation of dopamine-sensitive neurones in the rat substantia nigra pars compacta in vitro.选择性NK3受体激动剂森克肽在体外可兴奋大鼠黑质致密部中对多巴胺敏感的神经元亚群。

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