[避孕药类固醇引起的肝脏变化]

[Hepatic changes caused by contraceptive steroids].

作者信息

Uribe M, de Uribe M H, Carío A A

出版信息

Rev Gastroenterol Mex. 1977 Sep-Dec;42(3):139-47.

Abstract

The number and type of contraceptive side effects is constantly increasing. Several abnormalities have been observed regarding liver function, these include: Jaundice, cholestasis, hepatitis, changes in the rate synthesis of many serum proteins and coagulation factors. One of the most dangerous complications in the liver is the risk to develop hepatic adenoma which has been reported in 250 cases. An even more dangerous complication is the development of liver cancer of several histological types which so far has been observed in 21 patients. Women receiving contraceptive steroids should be alert regarding their potential hazards and the physician must be informed of such risks and observe special control care in these patients.

摘要

避孕副作用的数量和类型在不断增加。在肝功能方面已观察到几种异常情况，这些包括：黄疸、胆汁淤积、肝炎、许多血清蛋白和凝血因子合成速率的变化。肝脏中最危险的并发症之一是发生肝腺瘤的风险，已有250例报告。更危险的并发症是出现几种组织学类型的肝癌，到目前为止已在21名患者中观察到。接受避孕类固醇的女性应警惕其潜在危害，医生必须了解此类风险并对这些患者进行特殊的对照护理观察。