Arnold H, Fiebig H H
Radiologe. 1981 Sep;21(9):421-30.
Advanced malignant testicular tumors can be treated very successfully by chemotherapy. The most effective 3 or 4-drug combinations contain CisPlatin, Vinblastine, Bleomycin, Adriamycin, Cyclophosphamide, Ifosfamide and Vepesid. Complete remissions of 60% can be obtained; depending on histology, frequency of metastases, and former radiation therapy. Resection of residual pulmonary or retroperitoneal metastases render an additional 10-20% of the patients free of tumor. Side effects following chemotherapy should not be neglected: Depression of bone marrow, severe vomiting, alopecia, and azoospermia.
晚期恶性睾丸肿瘤可以通过化疗得到非常成功的治疗。最有效的三药或四药联合方案包含顺铂、长春碱、博来霉素、阿霉素、环磷酰胺、异环磷酰胺和依托泊苷。可以获得60%的完全缓解率；这取决于组织学类型、转移频率和既往放疗情况。切除残留的肺部或腹膜后转移灶可使另外10% - 20%的患者无瘤生存。化疗后的副作用不容忽视：骨髓抑制、严重呕吐、脱发和无精子症。
