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[在“金盏花素”消瘦模型中,亚硒酸钠、维生素E、去脂舒及其组合对不同年龄大鼠器官中三磷酸腺苷、磷酸肌酸和无机磷含量的影响]

[Effect of sodium selenite, vitamin E, retabolil and their combination on the ATP, creatine phosphate and inorganic phosphorus content of organs of rats of different ages in the "aurantin" model of hypotrophy].

作者信息

Mazgutov V Z, Makhmudov T M

出版信息

Vopr Pitan. 1981 Jul-Aug(4):37-41.

PMID:6170169
Abstract

The effect of sodium selenite, vitamin E, retabolil and their combinations on the content of ATP, creatine phosphate (CP) and inorganic phosphorus in the liver and skeletal muscle was studied in 3 groups of white rats (one- and two-month old and adults). Sodium selenite (30 micrograms/kg), vitamin E (50 mg/kg), retabolil (4 mg/kg) and their combination administered in a single subcutaneous dose for 14 days increased the content of ATP, CP and inorganic phosphorus in the liver and skeletal muscle after these parameters had decreased because of aurantine administration (50 micrograms/kg). Combined use of sodium selenite, vitamin E and retabolil appeared to be most efficacious.

摘要

研究了亚硒酸钠、维生素E、康力龙及其组合对三组白鼠(1月龄、2月龄和成年鼠)肝脏和骨骼肌中三磷酸腺苷(ATP)、磷酸肌酸(CP)和无机磷含量的影响。亚硒酸钠(30微克/千克)、维生素E(50毫克/千克)、康力龙(4毫克/千克)及其组合以单次皮下注射给药14天,在因给予奥丹定(50微克/千克)导致这些参数降低后,可提高肝脏和骨骼肌中ATP、CP和无机磷的含量。亚硒酸钠、维生素E和康力龙联合使用似乎最为有效。

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1
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