平阳霉素对外周淋巴细胞的作用。

Effect of pepleomycin on peripheral lymphocytes.

作者信息

Blomgren H, Edsmyr F, Strender L E

出版信息

Acta Radiol Oncol. 1981;20(2):113-8. doi: 10.3109/02841868109130430.

Abstract

The blood lymphocyte population was monitored in 6 patients with advanced malignant tumors who were treated with large doses of a new cytotoxic drug termed pepleomycin. It was observed that the size of the cell population, its cellular composition, mitogen stimulations and natural killer activity did not change in any consistent ways during or after treatment. It is concluded that pepleomycin does not directly affect the lymphocytic population.

摘要

对6例晚期恶性肿瘤患者进行了监测，这些患者接受了大剂量一种名为平阳霉素的新型细胞毒性药物治疗。观察到在治疗期间或治疗后，细胞群体的大小、细胞组成、有丝分裂原刺激和自然杀伤活性均未以任何一致的方式发生变化。得出的结论是，平阳霉素不会直接影响淋巴细胞群体。