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使用二维凝胶电泳检测人羊水蛋白质。

Detection of proteins in human amniotic fluid using two-dimensional gel electrophoresis.

作者信息

Jones M I, Spragg S P, Webb T

出版信息

Biol Neonate. 1981;39(3-4):171-7. doi: 10.1159/000241423.

DOI:10.1159/000241423
PMID:6170351
Abstract

Samples of human amniotic fluid from 48 pregnancies were examined by high resolution two-dimensional gel electrophoresis and the positions of the major peptides were mapped. Many of the proteins in amniotic fluid also occur in adult and fetal serum. Three regions in the amniotic fluid maps could be defined containing peptides which were not found in adult or fetal serum. The concentration of these peptides is variable and their origin is as yet unknown. Many differences were seen between adult and fetal serum proteins.

摘要

对48例妊娠的人羊水样本进行了高分辨率二维凝胶电泳检测,并绘制了主要肽段的位置图。羊水中的许多蛋白质也存在于成人和胎儿血清中。羊水图谱中有三个区域可被定义为含有在成人或胎儿血清中未发现的肽段。这些肽段的浓度各不相同,其来源尚不清楚。成人和胎儿血清蛋白之间存在许多差异。

相似文献

1
Detection of proteins in human amniotic fluid using two-dimensional gel electrophoresis.使用二维凝胶电泳检测人羊水蛋白质。
Biol Neonate. 1981;39(3-4):171-7. doi: 10.1159/000241423.
2
[Protein spectrum in the polyacrylamide gel of the blood serum of mother, fetus and amniotic fluid in physiologically proceeding pregnancy and labor].[生理状态下妊娠及分娩过程中母亲、胎儿血清及羊水聚丙烯酰胺凝胶中的蛋白质谱]
Vopr Okhr Materin Det. 1979 Jun;24(6):62-5.
3
Detection of novel fetal polypeptides in human amniotic fluid using two-dimensional gel electrophoresis.利用二维凝胶电泳检测人羊水中的新型胎儿多肽。
Tumour Biol. 1984;5(1):15-31.
4
Use of alpha-fetoprotein in prenatal diagnosis.甲胎蛋白在产前诊断中的应用。
Clin Obstet Gynecol. 1976 Dec;19(4):871-92. doi: 10.1097/00003081-197612000-00015.
5
Apolipoproteins in human fetal blood and amniotic fluid in mid-trimester pregnancy.孕中期人胎儿血液和羊水中的载脂蛋白。
Prenat Diagn. 1981 Apr;1(2):125-9. doi: 10.1002/pd.1970010207.
6
Alpha fetoprotein in pregnant women and in products of conception.孕妇及妊娠产物中的甲胎蛋白。
Indian J Med Res. 1980 Sep;72:374-80.
7
[Proteohormone concentrations in maternal and fetal blood as well as in the amniotic fluid at the moment of delivery (proceedings)].分娩时母血、胎儿血及羊水中蛋白激素浓度(会议论文集)
Arch Gynakol. 1977 Jul 29;224(1-4):122-3. doi: 10.1007/BF00679475.
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Biochemical and immunochemical identification of the fetal polypeptides of human amniotic fluid during the second trimester of pregnancy.妊娠中期人羊水胎儿多肽的生化及免疫化学鉴定
Braz J Med Biol Res. 1990;23(2):121-31.
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[Glycoproteins in maternal and fetal blood and amniotic fluid. Variations in normal and pathologic pregnancies].[母血、胎儿血液和羊水中的糖蛋白。正常和病理妊娠中的变化]
J Gynecol Obstet Biol Reprod (Paris). 1976 Jul-Aug;5(5):633-6.
10
[Differentiation of dried blood stains of pregnant females, from fetal blood and amniotic fluid by determination of alpha fetoprotein].[通过测定甲胎蛋白鉴别孕妇干血渍与胎儿血液及羊水]
Z Rechtsmed. 1988;101(1):9-13. doi: 10.1007/BF00205318.

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