Chamova K G, Perelaznyĭ A A, Guseva N I
Biull Eksp Biol Med. 1981 Jul;92(7):60-2.
Active antisera containing antibodies to deproteinized DNA preparations of mouse normal and leukemic tissues have been obtained. Examination of antisera by the quantitative complement fixation test with the corresponding test antigens has demonstrated immunological specificity of DNA preparations isolated from the organs of mice with leukemia induced by oncornaviruses. The DNA specificity in question is inherent not only in the native but also in the thermodenatured molecule of DNA.
已获得含有针对小鼠正常组织和白血病组织脱蛋白DNA制剂抗体的活性抗血清。通过使用相应测试抗原的定量补体结合试验对抗血清进行检测,结果表明,从肿瘤病毒诱导的白血病小鼠器官中分离出的DNA制剂具有免疫特异性。上述DNA特异性不仅存在于天然DNA分子中,也存在于热变性的DNA分子中。