Guberniev M A, Chamova K G, Perelaznii A A, Shumilova S L
J Hyg Epidemiol Microbiol Immunol. 1975;19(2):230-6.
Active antisera containing antibodies to deproteinized DNA preparations of normal tissue and the spleen of cows suffering from myeloleukosis were obtained. The anti DNA sera to DNA preparations contained complement fixing antibodies related to gamma M globulins. In the study of leukosis and normal anti DNA sera in quantitative CFR with the corresponding test antigens, immunological specificity of DNA preparations isolated from the organs of cows affected with myeloleukosis was established. Immunological specificity of leukosis DNA was confirmed in tests with the absorption of leukosis anti DNA sera by DNA preparations of homologous normal tissues. This specificity is an inherent quality of not only the native but also the heat-denatured DNA molecule.
获得了含有针对正常组织及患骨髓白血病奶牛脾脏的脱蛋白DNA制剂抗体的活性抗血清。针对DNA制剂的抗DNA血清含有与γM球蛋白相关的补体结合抗体。在用相应测试抗原进行的定量补体结合反应（CFR）中研究白血病抗血清和正常抗DNA血清时，确定了从患骨髓白血病奶牛器官中分离出的DNA制剂的免疫特异性。通过用同源正常组织的DNA制剂吸收白血病抗DNA血清进行的试验，证实了白血病DNA的免疫特异性。这种特异性不仅是天然DNA分子的固有特性，也是热变性DNA分子的固有特性。
