Iijima T
Cell Tissue Res. 1981;220(2):427-33. doi: 10.1007/BF00210519.
The uranaffin reaction in rat anococcygeus muscle, which receives a dual innervation of both adrenergic and non-cholinergic, non-adrenergic nerves was examined. Dense reaction product was observed in the vesicular membranes and/or the cores of some synaptic vesicles in the adrenergic nerve terminals. Occasional vesicles were filled up with dense reaction product. In the prominent population of small clear vesicles, however, no dense reaction product was observed. The number of small granular vesicles in the adrenergic nerve terminals was markedly increased after the administration of 5-hydroxydopamine (5-OHDA). These granular vesicles were moderately stained with uranaffin deposit on the cores but their limiting membranes possessed no uranaffin deposit at all. In the non-adrenergic nerve terminals, on the other hand, uranaffin deposit of variable density was observed on the cores of large granular vesicles but never on their limiting membranes or on the small clear vesicles. There was no change in the axon profiles after the administration of 5-OHDA. The possible occurrence of purines in the cores of large granular vesicles in the non-adrenergic nerves is discussed.
对大鼠肛门尾骨肌中的铀亲和反应进行了研究，该肌肉接受肾上腺素能神经和非胆碱能、非肾上腺素能神经的双重支配。在肾上腺素能神经末梢的一些突触小泡的泡膜和/或泡芯中观察到致密反应产物。偶尔有小泡充满致密反应产物。然而，在大量明显的清亮小泡中，未观察到致密反应产物。给予5-羟多巴胺（5-OHDA）后，肾上腺素能神经末梢中小颗粒小泡的数量明显增加。这些颗粒小泡的泡芯被铀亲和沉积物适度染色，但其界膜完全没有铀亲和沉积物。另一方面，在非肾上腺素能神经末梢，在大颗粒小泡的泡芯上观察到密度可变的铀亲和沉积物，但在其界膜或清亮小泡上从未观察到。给予5-OHDA后轴突轮廓没有变化。讨论了非肾上腺素能神经中大颗粒小泡泡芯中可能存在嘌呤的情况。
