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二聚体造影剂注入兔冠状动脉时的离子组成与心脏毒性

Ionic composition and cardiotoxicity of dimeric contrast media at injection into the coronary arteries of rabbits.

作者信息

Carter A M, Olin T

出版信息

Acta Radiol Diagn (Stockh). 1976 Jul;17(4):433-8. doi: 10.1177/028418517601700407.

DOI:10.1177/028418517601700407
PMID:61709
Abstract

The relation between ionic composition and cardiotoxicity of two dimers, iocarmate and iozomate, was investigated by selective injection into the left and right coronary arteries, Least toxic reactions developed at a sodium concentration of 263 to 315 mmol/l for sodium-meglumine iocarmate and 271 to 379 mmol/l for sodium-meglumine iozomate.

摘要

通过选择性注入左、右冠状动脉，研究了两种二聚体碘卡明和碘克沙醇的离子组成与心脏毒性之间的关系。对于碘卡明葡甲胺，在钠浓度为263至315 mmol/L时产生的毒性反应最小；对于碘克沙醇葡甲胺，在钠浓度为271至379 mmol/L时产生的毒性反应最小。

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