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氨基酸和核酸之间存在结构上的相似性吗?

Are there structural analogies between amino acids and nucleic acids?

作者信息

Hendry L B, Bransome E D, Petersheim M

出版信息

Orig Life. 1981 Sep;11(3):203-21. doi: 10.1007/BF00931386.

DOI:10.1007/BF00931386
PMID:6170923
Abstract

Space-filling molecular models have been used to examine structural analogies between amino acids and nucleic acids. The three-dimensional structures of amino acid R groups appear to be stereochemically related to cavities formed by removal of single bases in double helical nucleic acids. The common L amino acids may thus be complementary to their codons.

摘要

空间填充分子模型已被用于研究氨基酸和核酸之间的结构相似性。氨基酸R基团的三维结构在立体化学上似乎与双螺旋核酸中单个碱基去除后形成的空洞相关。因此,常见的L型氨基酸可能与其密码子互补。

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Are there structural analogies between amino acids and nucleic acids?氨基酸和核酸之间存在结构上的相似性吗?
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2
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引用本文的文献

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First approximation of a stereochemical rationale for the genetic code based on the topography and physicochemical properties of "cavities" constructed from models of DNA.基于由DNA模型构建的“腔”的拓扑结构和物理化学性质,对遗传密码进行立体化学原理的首次近似。
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3
An estimate on the effect of point mutation and natural selection on the rate of amino acid replacement in proteins.

本文引用的文献

1
Chemical specificity of nucleic acids and mechanism of their enzymatic degradation.核酸的化学特异性及其酶促降解机制。
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关于点突变和自然选择对蛋白质中氨基酸替换率影响的估计。
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Stereochemical relationship between coding triplets and amino-acids.编码三联体与氨基酸之间的立体化学关系。
Nature. 1966 Feb 26;209(5026):868-70. doi: 10.1038/209868a0.
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Origin of the genetic code.遗传密码的起源。
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A suggestion on the origin of the genetic code.
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The origin of the genetic code.遗传密码的起源。
Biochem Biophys Res Commun. 1970 Sep 30;40(6):1289-96. doi: 10.1016/0006-291x(70)90006-9.