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平均红细胞体积(MCV)和血清γ-谷氨酰转移酶(γ-GT)作为过量饮酒者筛查试验的比较效率(作者译)

[Compared efficiency of mean corpuscular volume (MCV) and serum gamma-glutamyltransferase (gamma-GT) as screening tests for excess-ethanol drinkers (author's transl)].

作者信息

Baglin M C, Bernot J L, Bremond J L, Lamy J, Leroux M E, Weill J

出版信息

Clin Chim Acta. 1976 May 3;68(3):321-6. doi: 10.1016/0009-8981(76)90398-3.

Abstract

53 percent of ethanol drinkers had, before detoxication, a gamma-GT higher than the upper limit of the reference interval at the 2.5 percent risk level (36 mU/ml). 44 percent had a mean corpuscular volume (MCV) higher than the limit (99.2 mum3). In alcoholics not previously "weaned" during a rest cure or in a hospital the proportion becomes 67 percent for gamma-GT but remains at 44 percent for MCV. gamma-GT thus seems a better test for the screening of an excessive ethanol intake than MCV, especially when the subject has not been previously weaned.

摘要

53%的饮酒者在戒酒前,其γ-谷氨酰转移酶(gamma-GT)高于参考区间上限(在2.5%风险水平时为36 mU/ml)。44%的饮酒者平均红细胞体积(MCV)高于上限(99.2立方微米)。在之前未在疗养或住院期间“戒酒”的酗酒者中,γ-谷氨酰转移酶升高的比例为67%,但平均红细胞体积升高的比例仍为44%。因此,γ-谷氨酰转移酶似乎比平均红细胞体积更适合用于筛查过量乙醇摄入,尤其是当受试者之前未戒酒时。

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