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[炎症病灶的肥大细胞系统与肾上腺皮质束状带之间的联系]

[Connections between the mast cell system of a focus of inflammation and the zona fasciculata of the adrenal cortex].

作者信息

Vasil'tsov M K, Trunova A I

出版信息

Arkh Anat Gistol Embriol. 1981 Sep;81(9):98-106.

PMID:6172098
Abstract

At aseptic inflammation developing around a solid foreign body and proceeding both under common conditions and on the background of disturbed inactivation of free amines as a result of monoaminoxidase blockade with vetrasin or devastation of amine tissue depots with reserpine it has been stated that indices of the adrenal cortex activity (hyperemia, contents of ascorbic acid and corticoids) and those of the mast cells system in the inflammatory focus (amount of the cells, their size, contents of glycosaminoglycans, RNA, tryptophan and histidine) are subjected to certain fluctuations during inflammation. Increasing activity of the adrenal cortex fascicular zone and renewal of the mast cell population in the inflammatory focus are directly proportional to the degree of a disturbed deposition of free amines in the organism. Certain positive correlations prevail in cooperation of the adrenal cortex activity, decomposition rate of large (mature) mast cells and migration into the inflammatory focus of small (immature) forms of these cells.

摘要

在围绕固体异物形成的无菌性炎症中,无论是在正常条件下,还是在因用维屈嗪阻断单胺氧化酶而导致游离胺失活受干扰,或因利血平破坏胺组织储存库的背景下发生的炎症中,都已表明,肾上腺皮质活动指标(充血、抗坏血酸和皮质激素含量)以及炎症灶中肥大细胞系统指标(细胞数量、大小、糖胺聚糖、RNA、色氨酸和组氨酸含量)在炎症过程中会发生一定波动。肾上腺皮质束状带活动的增加以及炎症灶中肥大细胞群体的更新与机体中游离胺沉积受干扰的程度成正比。肾上腺皮质活动、大(成熟)肥大细胞的分解速率与这些细胞的小(未成熟)形式向炎症灶的迁移之间的合作存在一定的正相关。

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Arkh Anat Gistol Embriol. 1981 Sep;81(9):98-106.
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