Fitzgerald T
Bull World Health Organ. 1981;59(5):787-101.
In vitro cultivation of Treponema pallidum would facilitate many different aspects of syphilis research. This review summarizes developments in this field that have been published since 1975. Findings are discussed in terms of treponemes and the oxygen question, treponemal metabolism involving proteins, nucleic acids, and fatty acids, and treponemal interaction with tissue culture cells. Suggested future approaches and potential problem areas pertinent to successful cultivation are discussed.
梅毒螺旋体的体外培养将有助于梅毒研究的许多不同方面。本综述总结了自1975年以来该领域已发表的进展。从密螺旋体与氧气问题、涉及蛋白质、核酸和脂肪酸的密螺旋体代谢以及密螺旋体与组织培养细胞的相互作用等方面对研究结果进行了讨论。还讨论了与成功培养相关的未来建议方法和潜在问题领域。
