Lutz-Ostertag Y
Arch Anat Microsc Morphol Exp. 1981;70(3):161-88.
The effect of lindane commercial solution spraying on quail eggs is studied in four generations running issued from a single parental strain. Observations have been made on fourteen-day embryos, one-day chicken and also two-or eight-month adults quail. The results lead to conclude that pathogenous effects of lindane on gonads and müllerian tract are slowly annuled through successive generations when the experimental procedure consists in treating only the parental eggs. Conversely, following pesticide administration repeated at every generation, the action becomes cumulative and the ratio of aberrations increases. In ovarian and testicular tissues there are cyto-histopathological modifications. Many gonocytes are abnormal and cannot divide. Some of these cells degenerate at the meiotic prophase. Egg production and fertility in adults depend on these phenomenons.
研究了林丹商业溶液喷洒对源自单一亲本菌株的连续四代鹌鹑蛋的影响。对14天龄胚胎、1日龄雏鸡以及2个月或8个月龄成年鹌鹑进行了观察。结果表明,当实验程序仅包括处理亲本蛋时,林丹对性腺和苗勒氏管的致病作用会在连续几代中缓慢消除。相反,若每一代都重复施用农药,其作用会累积,畸变率会增加。在卵巢和睾丸组织中存在细胞组织病理学改变。许多生殖细胞异常,无法分裂。其中一些细胞在减数分裂前期退化。成年鹌鹑的产蛋量和繁殖力取决于这些现象。