人γ干扰素的分子量与其他人干扰素的分子量相似。

Molecular weight of human gamma interferon is similar to that of other human interferons.

作者信息

Yip Y K, Barrowclough B S, Urban C, Vilcek J

出版信息

Science. 1982 Jan 22;215(4531):411-3. doi: 10.1126/science.6173921.

Abstract

The molecular weight (as determined by molecular sieve chromatography) of human gamma interferon, formerly referred to as immune or type II interferon, is between 40,000 and 70,000. On sodium dodecyl sulfate-polyacrylamide gel electrophoresis, gamma interferon activity was recovered mainly from two regions of the gels corresponding to molecular weights of 20,000 and 25,000. The results suggest that in native form human gamma interferon may be aggregated.

摘要

人γ干扰素的分子量（通过分子筛色谱法测定），以前称为免疫干扰素或II型干扰素，在40,000至70,000之间。在十二烷基硫酸钠-聚丙烯酰胺凝胶电泳上，γ干扰素活性主要从凝胶上对应分子量为20,000和25,000的两个区域回收。结果表明，天然形式的人γ干扰素可能是聚集的。