Zoon K C, Smith M E, Bridgen P J, zur Nedden D, Anfinsen C B
Proc Natl Acad Sci U S A. 1979 Nov;76(11):5601-5. doi: 10.1073/pnas.76.11.5601.
One component of human lymphoblastoid interferon obtained from Namalwa cultures induced by Newcastle disease virus has been purified to a specific activity of 2.5 x 10(8) interferon units per mg of protein (protein content based on amino acid analysis). A single polypeptide species with an apparent molecular weight of 18,500 comigrating with the antiviral activity was observed by sodium dodecyl sulfate/polyacrylamide gel electrophoresis. Preliminary amino-terminal sequencing results support the conclusion that the interferon species is essentially homogeneous.
从经新城疫病毒诱导的Namalwa培养物中获得的人淋巴母细胞样干扰素的一个组分已被纯化至比活性为每毫克蛋白质2.5×10⁸干扰素单位（基于氨基酸分析的蛋白质含量）。通过十二烷基硫酸钠/聚丙烯酰胺凝胶电泳观察到一种表观分子量为18,500且与抗病毒活性共迁移的单一多肽物种。初步的氨基末端测序结果支持该干扰素物种基本均一的结论。
